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M2-型丙酮酸激酶(PKM2)單克隆抗體

Monoclonal Antibody to Pyruvate kinase isozymes M2 (PKM2)

M2PK; PKM; M2-PK; PKM1; CTHBP; OIP3; PK3; PKM; TCB; THBP1; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Cytosolic thyroid hormone-binding protein; Pyruvate Kinase, Muscle

  • M2-型丙酮酸激酶(PKM2)單克隆抗體 產(chǎn)品包裝(模擬)
  • M2-型丙酮酸激酶(PKM2)單克隆抗體 產(chǎn)品包裝(模擬)
  • M2-型丙酮酸激酶(PKM2)單克隆抗體 Western Blot; Samples: Lane1: A549 cell lysate; Lane2: 293T cell lysate; Lane3: NIH/3T3 cell lysate;
    Primary Ab: 0.2μg/ml Mouse Anti-Human PKM2 Antibody
    Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate 通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對PKM2的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識別PKM2。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

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編號 適用物種：Homo sapiens (Human，人) 應(yīng)用(僅供研究使用，不用于臨床診斷！)
URPA588Hu01 M2-型丙酮酸激酶(PKM2)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
URPA588Hu02 M2-型丙酮酸激酶(PKM2)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
URPA588Hu03 M2-型丙酮酸激酶(PKM2)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
UAPA588Hu02 M2-型丙酮酸激酶(PKM2)活性蛋白 Cell?culture;?Activity?Assays.
UPAA588Hu02 M2-型丙酮酸激酶(PKM2)多克隆抗體 WB; IHC; ICC/IF; FCM
UPAA588Hu03 M2-型丙酮酸激酶(PKM2)多克隆抗體 WB; IHC; ICC/IF
UPAA588Hu01 M2-型丙酮酸激酶(PKM2)多克隆抗體 WB; IHC; ICC/IF; FCM
UFAA588Hu01 抗M2-型丙酮酸激酶(PKM2)多克隆抗體 FCM
UFAA588Hu03 抗M2-型丙酮酸激酶(PKM2)多克隆抗體 FCM
UMAA588Hu24 M2-型丙酮酸激酶(PKM2)單克隆抗體 WB
UMAA588Hu22 M2-型丙酮酸激酶(PKM2)單克隆抗體 WB
UMAA588Hu23 M2-型丙酮酸激酶(PKM2)單克隆抗體 WB; ICC/IF
UMAA588Hu21 M2-型丙酮酸激酶(PKM2)單克隆抗體 WB
USEA588Hu M2-型丙酮酸激酶(PKM2)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) Enzyme-linked immunosorbent assay for Antigen Detection.
ULMA588Hu M2-型丙酮酸激酶(PKM2)等多因子檢測試劑盒(流式熒光發(fā)光法) FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志 參考文獻(xiàn)
Cancer Research Antigen Presentation by Dendritic Cells in Tumors Is Disrupted by Altered Metabolism that Involves Pyruvate Kinase M2 and Its Interaction with SOCS3 [AACR: 70189]
Molecular BioSystems Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer [Pubmed:25483567]
Tumour Biol M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh’s ESCC and promotes proliferation and migration of ESCC cells [PubMed: 26404132]
Oncotarget Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis [Pubmed:29707118]
Journal of?Neurotrauma Acteoside improves muscle atrophy and motor function by inducing new myokine secretion in chronic spinal cord injury [Pubmed: 30318996]
Cell Reports Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway [Pubmed: 32049010]
Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) []
Cancer Cell International Bufalin Induced Mitochondrial Dysfunction Promotes Apoptosis of Glioma Cells by Regulating Annexin A2 and DRP1 Proteins []
Cancer Cell Int Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression [34376212]
Life (Basel) Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib [34947916]
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